Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915214 | 0.88 | HSD17B1 (0.36) | HSD17B1HSD17B2 | |
| SCHEMBL21915290 | 0.86 | HSD17B1 (0.45) | HSD17B1HSD17B2KDM4E | |
| SCHEMBL21915204 | 0.83 | HSD17B1 (0.38) | HSD17B1HSD17B2TP53KDM4E | |
| SCHEMBL21915611 | 0.82 | HSD17B1 (0.40) | HSD17B1HSD17B2 | |
| SCHEMBL21915205 | 0.80 | HSD17B1 (0.40) | HSD17B1HSD17B2TP53KDM4E | |
| SCHEMBL23196901 | 0.76 | TP53 (0.32) | TP53KDM4E | |
| SCHEMBL19129946 | 0.75 | PDE6D (0.31) | HPSE | |
| SCHEMBL21915199 | 0.75 | HSD17B1 (0.40) | HSD17B1HSD17B2 | |
| SCHEMBL21915553 | 0.73 | HSD17B1 (0.36) | HSD17B1HSD17B2KDM4E | |
| SCHEMBL23196854 | 0.73 | KDM4E (0.31) | TP53KDM4EHPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |