Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17297019 | 0.84 | GPR3 (0.61) | GPR3MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL18575925 | 0.81 | HPGD (0.36) | MAPTKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL19652587 | 0.81 | GPR3 (0.57) | GPR3MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL19537846 | 0.80 | GPR3 (0.55) | GPR3MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL15248355 | 0.80 | KDM4E (0.60) | GPR3MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL19652598 | 0.80 | GPR3 (0.55) | GPR3MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL21915323 | 0.79 | GPR3 (0.40) | GPR3MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL15964264 | 0.79 | MAPT (0.56) | MAPTKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL15248302 | 0.77 | GPR3 (0.61) | GPR3MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL23988585 | 0.77 | GPR3 (0.52) | GPR3MAPTKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |