Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915424 | 0.96 | MAPT (0.40) | MAPTSNCACYP19A1HSD17B1HSD17B2 | |
| SCHEMBL21915514 | 0.92 | MAPT (0.37) | MAPTSNCACYP19A1HSD17B1HSD17B2 | |
| SCHEMBL21916433 | 0.89 | F2 (0.37) | MAPTSNCACYP19A1HSD17B1HSD17B2 | |
| SCHEMBL17640487 | 0.88 | CYP19A1 (0.50) | MAPTSNCACYP19A1HSD17B1HSD17B2 | |
| SCHEMBL21915858 | 0.87 | HSD17B1 (0.38) | MAPTSNCACYP19A1HSD17B1HSD17B2 | |
| SCHEMBL21915289 | 0.86 | HSD17B1 (0.46) | MAPTSNCACYP19A1HSD17B1HSD17B2 | |
| SCHEMBL21916394 | 0.84 | MAPT (0.32) | MAPTSNCACYP19A1HSD17B1HSD17B2 | |
| SCHEMBL21915412 | 0.82 | KDM4E (0.38) | MAPTSNCACYP19A1HSD17B1HSD17B2 | |
| SCHEMBL21915369 | 0.82 | MAPT (0.37) | MAPTSNCACYP19A1HSD17B1HSD17B2 | |
| SCHEMBL17640568 | 0.81 | CYP19A1 (0.45) | MAPTSNCACYP19A1HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |