Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915584 | 0.91 | HSD17B1 (0.31) | MAPTSNCAHSD17B1HSD17B2HDAC6 | |
| SCHEMBL21915415 | 0.88 | HDAC6 (0.31) | HDAC6 | |
| SCHEMBL21915543 | 0.87 | PTGER4 (0.37) | MAPTSNCAHSD17B1HSD17B2CYP19A1 | |
| SCHEMBL21916407 | 0.85 | MAPT (0.34) | MAPTSNCAHSD17B1HSD17B2CYP19A1 | |
| SCHEMBL21915203 | 0.85 | MAPT (0.34) | MAPTSNCAHSD17B1HSD17B2CYP19A1 | |
| SCHEMBL21915533 | 0.84 | MAPT (0.34) | MAPTSNCAHSD17B1HSD17B2CYP19A1 | |
| SCHEMBL17640548 | 0.83 | CYP19A1 (0.47) | MAPTSNCAHSD17B1HSD17B2HDAC6 | |
| SCHEMBL21915593 | 0.82 | HSD17B1 (0.31) | HSD17B1HSD17B2 | |
| SCHEMBL17278622 | 0.81 | HDAC6 (0.40) | MAPTHDAC6PTGER4AHRKDM4E | |
| SCHEMBL21915544 | 0.81 | HSD17B1 (0.39) | MAPTSNCAHSD17B1HSD17B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |