Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | PDE6D | O43924 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915234 | 0.90 | HSD17B1 (0.43) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21915473 | 0.88 | CYP19A1 (0.41) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21915395 | 0.86 | HSD17B1 (0.40) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21916391 | 0.85 | CYP19A1 (0.44) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21915624 | 0.85 | HSD17B1 (0.39) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21915232 | 0.84 | HSD17B1 (0.40) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21915581 | 0.84 | HSD17B1 (0.41) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21915839 | 0.82 | HSD17B1 (0.48) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21915834 | 0.81 | HSD17B1 (0.51) | HSD17B1HSD17B2MAPTSNCACYP19A1 | |
| SCHEMBL21915470 | 0.81 | HSD17B1 (0.54) | HSD17B1HSD17B2MAPTSNCACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |