Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915458 | 0.94 | HSD17B1 (0.37) | HSD17B1HSD17B2MAPTSNCACA12 | |
| SCHEMBL21915888 | 0.93 | HSD17B1 (0.39) | HSD17B1HSD17B2MAPTSNCAKDM4E | |
| SCHEMBL21915249 | 0.92 | HSD17B1 (0.37) | HSD17B1HSD17B2MAPTSNCAKDM4E | |
| SCHEMBL21915250 | 0.92 | HSD17B1 (0.38) | HSD17B1HSD17B2MAPTSNCACA12 | |
| SCHEMBL21915271 | 0.92 | HSD17B1 (0.45) | HSD17B1HSD17B2MAPTSNCAPDE10A | |
| SCHEMBL21915523 | 0.91 | HSD17B1 (0.38) | HSD17B1HSD17B2MAPTSNCACA12 | |
| SCHEMBL21915401 | 0.90 | HSD17B1 (0.45) | HSD17B1HSD17B2MAPTSNCAPDE10A | |
| SCHEMBL21915399 | 0.89 | HSD17B1 (0.48) | HSD17B1HSD17B2MAPTSNCAPDE10A | |
| SCHEMBL21915522 | 0.88 | HSD17B1 (0.41) | HSD17B1HSD17B2MAPTSNCAPDE10A | |
| SCHEMBL21916395 | 0.87 | HSD17B1 (0.34) | HSD17B1HSD17B2CYP19A1TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |