Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.80 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19279561 | 0.89 | BTK (1.00) | BTKJAK2 | |
| SCHEMBL19279587 | 0.88 | BTK (1.00) | BTK | |
| SCHEMBL21917300 | 0.83 | BTK (0.63) | BTK | |
| SCHEMBL19279632 | 0.82 | BTK (1.00) | BTK | |
| SCHEMBL19279572 | 0.74 | BTK (1.00) | BTK | |
| SCHEMBL19279541 | 0.74 | BTK (1.00) | BTK | |
| SCHEMBL19279550 | 0.74 | BTK (1.00) | BTK | |
| SCHEMBL24192297 | 0.74 | BTK (0.78) | BTK | |
| SCHEMBL21509027 | 0.73 | BTK (0.80) | BTK | |
| SCHEMBL19279151 | 0.72 | BTK (1.00) | BTKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209652-B1 | TRICYCLIC ATROPISOMER COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-04-15 | — | — | EP | disclosed |