Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17123642 | 0.82 | TLR7 (0.42) | TLR7TLR8KCNH2 | |
| SCHEMBL20025838 | 0.76 | TLR7 (0.43) | TLR7TLR8KCNH2TRPM8 | |
| SCHEMBL22825028 | 0.76 | TLR7 (0.43) | TLR7TLR8KCNH2TRPM8 | |
| SCHEMBL21693478 | 0.75 | TLR7 (0.50) | TLR7TLR8KCNH2TRPM8 | |
| SCHEMBL23185623 | 0.73 | TLR7 (0.43) | TLR7TLR8 | |
| SCHEMBL13195729 | 0.72 | TLR7 (0.54) | TLR7TLR8KCNH2 | |
| SCHEMBL20219473 | 0.72 | TLR7 (0.54) | TLR7TLR8KCNH2 | |
| SCHEMBL13195694 | 0.72 | TLR7 (0.54) | TLR7TLR8KCNH2 | |
| SCHEMBL17123641 | 0.72 | P2RX3 (0.41) | TLR7TLR8KCNH2TRPM8 | |
| SCHEMBL23472404 | 0.72 | TLR7 (0.51) | TLR7TLR8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903967-B3 | ACYLAMINOPYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2020-04-15 | — | — | EP | disclosed |