SCHEMBL2191952

SCHEMBL2191952

CNCCCC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3641708 0.92
SCHEMBL7282574 0.89 TSHR (0.52)
SCHEMBL7380826 0.89
SCHEMBL13624929 0.89 TSHR (0.52)
SCHEMBL7293332 0.89 TSHR (0.52)
SCHEMBL7292979 0.89 TSHR (0.52)
SCHEMBL7284997 0.89 TSHR (0.52)
SCHEMBL7291233 0.89 TSHR (0.52)
SCHEMBL18567837 0.87 HIF1A (0.43)
SCHEMBL566259 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12480131-B2 Tropane alkaloid (TA) producing non-plant host cells, and methods of making and using the same THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-11-25 US claimed
CN-113784758-B Non-plant host cells producing tropane alkaloids (TA) and methods of making and using the same 小利兰·斯坦福大学托管委员会 2025-03-07 CN claimed
US-20240191267-A1 Tropane Alkaloid Transporters and Methods of Making Tropane Alkaloids Using the Same HERCULES CAPITAL, INC., AS AGENT 2024-06-13 US claimed
CN-118119609-A Imidazole derivatives and their use as antibiotics 豪夫迈·罗氏有限公司 2024-05-31 CN claimed
EP-4314301-A1 TROPANE ALKALOID TRANSPORTERS AND METHODS OF MAKING TROPANE ALKALOIDS USING THE SAME The Board of Trustees of the Leland Stanford Junior University (US) 2024-02-07 EP claimed
CN-117500928-A Tropane alkaloid transporter and method for producing tropane alkaloid using same 小利兰·斯坦福大学托管委员会 2024-02-02 CN claimed
WO-2022204283-A1 TROPANE ALKALOID TRANSPORTERS AND METHODS OF MAKING TROPANE ALKALOIDS USING THE SAME THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-09-29 WO claimed
US-20220170026-A1 TROPANE ALKALOID (TA) PRODUCING NON-PLANT HOST CELLS, AND METHODS OF MAKING AND USING THE SAME HERCULES CAPITAL, INC., AS AGENT 2022-06-02 US claimed
EP-3934765-A1 TROPANE ALKALOID (TA) PRODUCING NON-PLANT HOST CELLS, AND METHODS OF MAKING AND USING THE SAME The Board Of Trustees Of The Leland Stanford Junior University (US) 2022-01-12 EP claimed
CN-113784758-A Non-plant host cells that produce Tropane Alkaloids (TA) and methods of making and using the same 小利兰·斯坦福大学托管委员会 2021-12-10 CN claimed
WO-2020185626-A1 TROPANE ALKALOID (TA) PRODUCING NON-PLANT HOST CELLS, AND METHODS OF MAKING AND USING THE SAME THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2020-09-17 WO claimed
CN-103946233-A Polymyxin derivatives NOVACTA BIOSYSTEMS LTD 2014-07-23 CN claimed
US-6380197-B1 FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES AVENTIS PHARMA S. A. (FR) 2002-04-30 US claimed
EP-1001943-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM Aventis Pharma S.A. (FR) 2000-05-24 EP claimed
WO-1999003843-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM RHONE-POULENC RORER S.A. (FR) 1999-01-28 WO claimed
EP-4662209-A1 CONJUGATE COMPOUNDS AND COMPOSITIONS Rezubio Pharmaceuticals Co., Ltd (CN) 2025-12-17 EP disclosed
US-12480131-B2 Tropane alkaloid (TA) producing non-plant host cells, and methods of making and using the same THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-11-25 US disclosed
EP-0418696-A2 Derivatives of aminoacids MERCK PATENT GmbH (DE) 1991-03-27 EP disclosed
CN-1037155-A Amino acid derivative MERCK PATENT GMBH (DE) 1989-11-15 CN disclosed
EP-0337334-A2 Renin-inhibiting amino acid derivatives MERCK PATENT GmbH (DE) 1989-10-18 EP disclosed