Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ADH1B | P00325 | 3/20 | 0.42 |
| ▸ | ADH1A | P07327 | 3/20 | 0.42 |
| ▸ | ADH7 | P40394 | 3/20 | 0.42 |
| ▸ | ADH1C | P00326 | 2/20 | 0.42 |
| ▸ | ADH4 | P08319 | 1/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380826 | 1.00 | — | — | |
| SCHEMBL7293332 | 1.00 | TSHR (0.52) | TSHREPHX1FAAHTRPV1HIF1A | |
| SCHEMBL7292979 | 1.00 | TSHR (0.52) | TSHREPHX1FAAHTRPV1HIF1A | |
| SCHEMBL7291233 | 1.00 | TSHR (0.52) | TSHREPHX1FAAHTRPV1HIF1A | |
| SCHEMBL7282574 | 1.00 | TSHR (0.52) | TSHREPHX1FAAHTRPV1HIF1A | |
| SCHEMBL7284997 | 1.00 | TSHR (0.52) | TSHREPHX1FAAHTRPV1HIF1A | |
| SCHEMBL3641708 | 0.97 | — | — | |
| SCHEMBL2191952 | 0.89 | — | — | |
| Acetic Acid SCHEMBL30784711 | 0.89 | TSHR (0.43) | TSHREPHX1FAAHTRPV1HIF1A | |
| SCHEMBL18900753 | 0.83 | FAAH (0.58) | TSHREPHX1FAAHTRPV1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138511-A1 | LONG-ACTING Y2 AND/OR Y4 RECEPTOR AGONISTS | NOVO NORDISK A/S (DK) | 2009-11-19 | — | — | WO | disclosed |