Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 11/20 | 0.54 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17758594 | 0.84 | NAAA (0.59) | NAAAASAH1CTSL | |
| SCHEMBL3709136 | 0.81 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL16652791 | 0.81 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL14771817 | 0.81 | KDM1A (0.52) | KDM1AMAOAMAOB | |
| SCHEMBL4567295 | 0.81 | KDM1A (0.52) | KDM1AMAOAMAOB | |
| SCHEMBL14771724 | 0.81 | KDM1A (0.52) | KDM1AMAOAMAOB | |
| SCHEMBL14771818 | 0.81 | KDM1A (0.52) | KDM1AMAOAMAOB | |
| SCHEMBL16253593 | 0.81 | KDM1A (0.52) | KDM1AMAOAMAOB | |
| SCHEMBL15280573 | 0.81 | KDM1A (0.52) | KDM1AMAOAMAOB | |
| SCHEMBL16253592 | 0.81 | KDM1A (0.52) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2849568-B1 | PROCESS FOR MAKING CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (US) | 2020-04-15 | — | — | EP | disclosed |