SCHEMBL21919804

SCHEMBL21919804

CCOP(=O)(CC(CCCOCc1ccccc1)C(=O)OC(C)(C)C)OCC

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.45
MMP3 P08254 5/20 0.41
MMP8 P22894 4/20 0.41
MMP9 P14780 3/20 0.41
PPARA Q07869 2/20 0.40
CETP P11597 3/20 0.40
MMP1 P03956 4/20 0.40
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
FOLH1 Q04609 1/20 0.39
SYK P43405 1/20 0.38
PPARG P37231 1/20 0.37
LTA4H P09960 1/20 0.37
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21804792 0.76 PPARD (0.40) MAPTMAPK1
SCHEMBL17533540 0.75 MAPT (0.39) MAPTMAPK1FOLH1HSD17B10
SCHEMBL27725067 0.74 L3MBTL1 (0.55) L3MBTL1MMP3MMP8MMP9PPARA
SCHEMBL27725065 0.74 L3MBTL1 (0.55) L3MBTL1MMP3MMP8MMP9PPARA
SCHEMBL1907332 0.74 PPARA (0.58) L3MBTL1MMP3PPARAMMP1MAPT
SCHEMBL1759186 0.74 POLB (0.46) L3MBTL1MMP3MMP8MMP9CETP
SCHEMBL29520381 0.74 FOLH1 (0.48) L3MBTL1PPARACETPMAPTMAPK1
SCHEMBL6293054 0.73 L3MBTL1 (0.50) L3MBTL1PPARAMAPK1SYKPPARG
SCHEMBL15684087 0.73 L3MBTL1 (0.51) L3MBTL1MMP3MMP8MMP9PPARA
SCHEMBL14243701 0.73 L3MBTL1 (0.51) L3MBTL1MMP3MMP8MMP9PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166087-B Screening agent and use thereof 恩多塞特公司 2024-05-10 CN disclosed
US-20210323985-A1 SHIELDING AGENTS AND THEIR USE ENDOCYTE INC (US) 2021-10-21 US disclosed
US-20210323985-A1 SHIELDING AGENTS AND THEIR USE ENDOCYTE INC (US) 2021-10-21 US disclosed
CN-113166087-A Shielding agent and application thereof 恩多塞特公司 2021-07-23 CN disclosed
WO-2020061293-A1 SHIELDING AGENTS AND THEIR USE ENDOCYTE, INC. (US) 2020-03-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210323985-A1 SHIELDING AGENTS AND THEIR USE PSMA6, PSMA2, PSMA1 L3MBTL1 723/4885MMP3 2307/4885MMP8 2507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.