Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 9/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5036773 | 0.83 | KDM1A (0.46) | KDM1ATSHRRAB9AALOX15MAPK1 | |
| SCHEMBL2272537 | 0.80 | LMNA (0.47) | KDM1ATSHRRAB9AALOX15MAPK1 | |
| SCHEMBL20467138 | 0.78 | KDM1A (0.40) | KDM1ATSHRRAB9AALOX15MAPK1 | |
| SCHEMBL435115 | 0.74 | KDM1A (0.46) | KDM1ATSHRRAB9AALOX15MAPK1 | |
| SCHEMBL5041555 | 0.72 | NTRK1 (0.44) | KDM1ATSHRRAB9AALOX15MAPK1 | |
| SCHEMBL5036813 | 0.72 | KDM1A (0.46) | KDM1ATSHRRAB9AALOX15MAPK1 | |
| SCHEMBL19236928 | 0.69 | TSHR (0.43) | KDM1ATSHRRAB9AALOX15MAPK1 | |
| SCHEMBL24188606 | 0.69 | KDM1A (0.41) | KDM1ATSHRRAB9AALOX15MAPK1 | |
| SCHEMBL19229614 | 0.69 | KDM1A (0.49) | KDM1ATSHRRAB9AALOX15MAPK1 | |
| SCHEMBL5036630 | 0.69 | MAPT (0.47) | KDM1ATSHRRAB9AMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632899-A1 | ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS CALCIUM OR SODIUM CHANNEL BLOCKERS | RaQualia Pharma Inc. (JP) | 2020-04-08 | — | — | EP | disclosed |