Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20231023 | 0.85 | CHRNB2 (0.38) | CHRNB2CHRNA4KMT2ACHRNB1CHRNB4 | |
| SCHEMBL506299 | 0.84 | CHRNB2 (0.42) | CHRNB2CHRNA4KMT2ACHRNB1CHRNB4 | |
| SCHEMBL20233868 | 0.83 | CHRNB2 (0.35) | CHRNB2CHRNA4KMT2ACHRNB1CHRNB4 | |
| SCHEMBL21182267 | 0.81 | CHRNB2 (0.40) | CHRNB2CHRNA4KMT2ACHRNB1CHRNB4 | |
| SCHEMBL26401540 | 0.79 | CHRNB2 (0.39) | CHRNB2CHRNA4KMT2ACHRNB1CHRNB4 | |
| SCHEMBL13020439 | 0.78 | CHRNB2 (0.45) | CHRNB2CHRNA4KMT2ACHRNB1CHRNB4 | |
| SCHEMBL26401405 | 0.78 | HTT (0.43) | CHRNB2CHRNA4KMT2ACHRNB1CHRNB4 | |
| SCHEMBL26401534 | 0.77 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 | |
| SCHEMBL20441137 | 0.76 | KMT2A (0.40) | CHRNB2CHRNA4KMT2ACHRNB1CHRNB4 | |
| SCHEMBL2669046 | 0.75 | NQO1 (0.56) | CHRNB2CHRNA4KMT2ACHRNB1CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632899-A1 | ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS CALCIUM OR SODIUM CHANNEL BLOCKERS | RaQualia Pharma Inc. (JP) | 2020-04-08 | — | — | EP | disclosed |