SCHEMBL219214

SCHEMBL219214

CCCCC1=Cc2ccccc2[CH]1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.36
SETD7 Q8WTS6 1/20 0.33
CES2 O00748 2/20 0.32
CES1 P23141 2/20 0.32
SIGMAR1 Q99720 1/20 0.32
SKP2 Q13309 1/20 0.32
PTPN1 P18031 1/20 0.32
TLR8 Q9NR97 1/20 0.32
HSD11B1 P28845 1/20 0.32
KCNH2 Q12809 1/20 0.31
NPC1 O15118 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27619013 0.98 LIPG (0.35) LIPGSETD7CES2CES1SIGMAR1
SCHEMBL3685992 0.94 LIPG (0.43) LIPGSETD7SIGMAR1PTPN1KCNH2
SCHEMBL27948576 0.93 LIPG (0.36) LIPGSETD7
SCHEMBL27948616 0.93 LIPG (0.33) LIPGSETD7
SCHEMBL27948720 0.93 LIPG (0.33) LIPGSETD7
SCHEMBL27619058 0.93 LIPG (0.33) LIPGSETD7
SCHEMBL27932885 0.93 LIPG (0.33) LIPGSETD7SKP2
SCHEMBL27933157 0.93 LIPG (0.33) LIPGSETD7SKP2
SCHEMBL27948778 0.93 LIPG (0.33) LIPGSETD7
SCHEMBL27933073 0.93 LIPG (0.33) LIPGSETD7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024033278-A1 PROCESS FOR MANUFACTURING AN ANTIBIOTIC MACROCYCLIC PEPTIDE F. HOFFMANN-LA ROCHE AG (CH) 2024-02-15 WO claimed
CN-108250340-B Metallocene catalyst system and method for catalyzing olefin polymerization by using same 北京引发科技有限公司 2021-03-19 CN claimed
CN-108250341-B Catalyst system containing metallocene compound and method for catalyzing olefin polymerization by using catalyst system 北京引发科技有限公司 2020-12-11 CN claimed
US-20140219911-A1 DIHYDROXYBIPYRIDINE COMPLEXES OF RUTHENIUM AND IRIDIUM FOR WATER OXIDATION AND HYDROGENATION THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2014-08-07 US claimed
WO-2013033018-A2 DIHYDROXYBIPYRIDINE COMPLEXES OF RUTHENIUM AND IRIDIUM FOR WATER OXIDATION AND HYDROGENATION DREXEL UNIVERSITY (US) 2013-03-07 WO claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
CN-1289554-C Polymerization process for producing copolymers of propylene BOREALIS POLYMERS OY (FI) 2006-12-13 CN claimed
US-7141527-B1 Catalyst system and process for the polymerization of olefins BASELL POLYOLEFINE GMBH (DE) 2006-11-28 US claimed
CN-1537123-A polymerization process for producing propylene copolymers 2004-10-13 CN claimed
CN-1157427-C Polymerization method for olefrines �����ɷ� 2004-07-14 CN claimed
CN-1374973-A Catalyst system and process for olefin polymerization BASSER TECHNOLOGY N V (NL) 2002-10-16 CN claimed
CN-1075076-C Metallocene compound, preparation method thereof and application thereof in olefin polymerization catalyst MONTELL TECHNOLOGY COMPANY BV (NL) 2001-11-21 CN claimed
CN-1260807-A Polymerization method for olefrines BOREALL AS (DK) 2000-07-19 CN claimed
CN-1150430-A Metallocene compound, preparation method thereof and application thereof in olefin polymerization catalyst MONTELL TECHNOLOGY COMPANY BV (NL) 1997-05-21 CN claimed
CN-117903217-A Phosphine-phenol single-chromocene metal complex, preparation method and application thereof 中国石油化工股份有限公司 2024-04-19 CN disclosed
CN-117903216-A Phosphine-phenol single metallocene complex and preparation method and application thereof 中国石油化工股份有限公司 2024-04-19 CN disclosed
WO-2024078525-A1 PHOSPHINE-PHENOL HALF-METALLOCENE COMPLEX, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油化工股份有限公司 2024-04-18 WO disclosed
US-5654454-A REDUCING UNSATURATED SUBSTITUENTS; USED FOR ADDITION POLYMERIZATION OF OLEFINS PHILLIPS PETROLEUM COMPANY (US) 1997-08-05 US disclosed
CN-1150430-A Metallocene compound, preparation method thereof and application thereof in olefin polymerization catalyst MONTELL TECHNOLOGY COMPANY BV (NL) 1997-05-21 CN disclosed
EP-0745607-A2 Metallocene preparation and use PHILLIPS PETROLEUM COMPANY (US) 1996-12-04 EP disclosed