Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CPS1 | P31327 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2134746 | 1.00 | FFAR1 (0.47) | FFAR1CYP4F2CYP4A11MTNR1AMTNR1B | |
| SCHEMBL2134742 | 1.00 | FFAR1 (0.47) | FFAR1CYP4F2CYP4A11MTNR1AMTNR1B | |
| SCHEMBL14480439 | 0.88 | FFAR1 (0.47) | FFAR1CYP4F2CYP4A11CPS1KMT2A | |
| SCHEMBL10289079 | 0.88 | FFAR1 (0.47) | FFAR1CYP4F2CYP4A11CPS1KMT2A | |
| SCHEMBL2133690 | 0.88 | FFAR1 (0.47) | FFAR1CYP4F2CYP4A11CPS1KMT2A | |
| SCHEMBL10288350 | 0.88 | FFAR1 (0.47) | FFAR1CYP4F2CYP4A11CPS1KMT2A | |
| SCHEMBL2968543 | 0.84 | MTNR1A (0.44) | FFAR1MTNR1AMTNR1BKMT2AMEN1 | |
| SCHEMBL2957759 | 0.84 | MTNR1A (0.60) | FFAR1MTNR1AMTNR1BKMT2AMEN1 | |
| SCHEMBL2135558 | 0.82 | CA1 (0.45) | FFAR1KMT2AMEN1 | |
| SCHEMBL2135553 | 0.82 | CA1 (0.45) | FFAR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632899-A1 | ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS CALCIUM OR SODIUM CHANNEL BLOCKERS | RaQualia Pharma Inc. (JP) | 2020-04-08 | — | — | EP | disclosed |