Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298561 | 0.92 | CA1 (0.38) | APEX1CA1CA2CA9CYP2C19 | |
| SCHEMBL29939280 | 0.92 | CA1 (0.38) | APEX1CA1CA2CA9CYP2C19 | |
| SCHEMBL13574881 | 0.91 | CA1 (0.37) | APEX1CA1CA2CA9CYP2C19 | |
| SCHEMBL205802 | 0.88 | CA1 (0.35) | APEX1CA1CA2CA9CYP2C19 | |
| SCHEMBL29355846 | 0.88 | CA1 (0.35) | APEX1CA1CA2CA9CYP2C19 | |
| SCHEMBL10039495 | 0.86 | TSHR (0.42) | APEX1CA1CA2CA9CYP2C19 | |
| SCHEMBL9298566 | 0.85 | PTGDR2 (0.38) | APEX1CA1CA2CA9CYP2C19 | |
| SCHEMBL7115234 | 0.84 | APEX1 (0.39) | APEX1CA1CA2CA9CYP2C19 | |
| SCHEMBL31556870 | 0.84 | APEX1 (0.39) | APEX1CA1CA2CA9CYP2C19 | |
| SCHEMBL14454211 | 0.84 | RARA (0.33) | APEX1CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958538-B1 | STABILIZED DENTAL IMPRESSION COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2020-04-29 | — | — | EP | disclosed |