Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.79 |
| ▸ | SLC10A2 | Q12908 | 3/20 | 0.79 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.79 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.70 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.70 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 9/20 | 0.69 |
| ▸ | CA2 | P00918 | 9/20 | 0.69 |
| ▸ | VDR | P11473 | 1/20 | 0.63 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19549224 | 1.00 | GPBAR1 (0.79) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL21925650 | 1.00 | GPBAR1 (0.79) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL19549230 | 1.00 | GPBAR1 (0.79) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL1977807 | 0.94 | GPBAR1 (0.80) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL19577615 | 0.94 | GPBAR1 (0.80) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL29406668 | 0.93 | GPBAR1 (0.68) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL14485302 | 0.92 | GPBAR1 (0.85) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL19549288 | 0.92 | GPBAR1 (0.79) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL19549290 | 0.92 | GPBAR1 (0.79) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL24098350 | 0.90 | GPBAR1 (0.91) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131223-A1 | COMPOUND FOR TREATING CLOSTRIDIUM DIFFICILE | INSIGHT HEALTH LIMITED | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131223-A1 | COMPOUND FOR TREATING CLOSTRIDIUM DIFFICILE | DSTN, DAD1, DDOST | GPBAR1 77/4885SLC10A2 13/4885ABCC4 464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.