Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.80 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.80 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.80 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.74 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.74 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | CA1 | P00915 | 9/20 | 0.72 |
| ▸ | CA2 | P00918 | 9/20 | 0.72 |
| ▸ | VDR | P11473 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19577615 | 1.00 | GPBAR1 (0.80) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL14485302 | 0.95 | GPBAR1 (0.85) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL21925650 | 0.94 | GPBAR1 (0.79) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL19549230 | 0.94 | GPBAR1 (0.79) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL19549224 | 0.94 | GPBAR1 (0.79) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL21923105 | 0.94 | GPBAR1 (0.79) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL25658157 | 0.92 | GPBAR1 (0.81) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL18199508 | 0.92 | GPBAR1 (0.81) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL14497558 | 0.91 | GPBAR1 (0.80) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL12250467 | 0.91 | GPBAR1 (0.80) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011070436-A2 | IN SITU CROSS LINKED BIODEGRADABLE GEL WITH HYDROPHOBIC POCKETS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-06-16 | — | — | WO | claimed |
| WO-2011070436-A2 | IN SITU CROSS LINKED BIODEGRADABLE GEL WITH HYDROPHOBIC POCKETS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-06-16 | — | — | WO | disclosed |