Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 20/20 | 0.68 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.56 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17896424 | 0.93 | MAP4K4 (0.68) | MAP4K4MINK1TNIK | |
| SCHEMBL1032209 | 0.90 | MAP4K4 (0.71) | MAP4K4MINK1TNIK | |
| SCHEMBL17896425 | 0.82 | MAP4K4 (0.72) | MAP4K4MINK1TNIK | |
| SCHEMBL15587252 | 0.81 | MAP4K4 (1.00) | MAP4K4MINK1TNIK | |
| SCHEMBL31060266 | 0.81 | MAP4K4 (1.00) | MAP4K4MINK1TNIK | |
| SCHEMBL18135276 | 0.80 | MAP4K4 (0.72) | MAP4K4MINK1TNIK | |
| SCHEMBL1035448 | 0.79 | MAP4K4 (0.74) | MAP4K4MINK1TNIK | |
| SCHEMBL15587457 | 0.78 | MAP4K4 (1.00) | MAP4K4MINK1TNIK | |
| SCHEMBL15587270 | 0.78 | MAP4K4 (1.00) | MAP4K4MINK1TNIK | |
| SCHEMBL21923095 | 0.77 | MAP4K4 (0.71) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855459-B1 | AMINOQUINAZOLINE AND PYRIDOPYRIMIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2020-04-29 | — | — | EP | disclosed |