SCHEMBL21923978

SCHEMBL21923978

c1ccc(-c2ccc(N(c3ccccc3)c3ccc4c(c3)C3(c5ccccc5-4)c4ccccc4-c4ccc(N(c5ccccc5)c5ccc6c(c5)c5ccccc5n6-c5ccccc5)cc43)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
TSPO P30536 1/20 0.33
PDK2 Q15119 2/20 0.31
HDAC4 P56524 1/20 0.31
KMT2A Q03164 2/20 0.30
IL1R1 P14778 1/20 0.30
PTGER4 P35408 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25563387 1.00 L3MBTL1 (0.39) L3MBTL1KDM4EATMTSPOPDK2
SCHEMBL12560106 0.99 L3MBTL1 (0.40) L3MBTL1KDM4EATMTSPOPDK2
SCHEMBL23595012 0.99 L3MBTL1 (0.40) L3MBTL1KDM4EATMTSPOPDK2
SCHEMBL19167913 0.98 L3MBTL1 (0.39) L3MBTL1KDM4EATMTSPOPDK2
SCHEMBL12560070 0.98 KDM4E (0.36) L3MBTL1KDM4EATMTSPOPDK2
SCHEMBL19166136 0.98 L3MBTL1 (0.39) L3MBTL1KDM4EATMTSPOPDK2
SCHEMBL13803229 0.96 KDM4E (0.38) L3MBTL1KDM4EATMTSPOPDK2
SCHEMBL13775015 0.96 KDM4E (0.38) L3MBTL1KDM4EATMTSPOPDK2
SCHEMBL13803233 0.96 KDM4E (0.38) L3MBTL1KDM4EATMTSPOPDK2
SCHEMBL13803671 0.96 KDM4E (0.38) L3MBTL1KDM4EATMTSPOPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020083327-A1 ORGANIC COMPOUND CONTAINING SPIROBIFLUORENE STRUCTURE AND APPLICATION THEREOF IN OLED DEVICE 常州强力电子新材料股份有限公司 2020-04-30 WO disclosed