Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | AGPAT2 | O15120 | 4/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.32 |
| ▸ | CCR9 | P51686 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21925109 | 0.89 | KDM4E (0.37) | KDM4EALDH1A1CYP1A2HPGDCYP2C9 | |
| SCHEMBL21925088 | 0.88 | NPC1 (0.33) | ALDH1A1 | |
| SCHEMBL22201108 | 0.88 | PDE2A (0.32) | KDM4ECYP2C9AGPAT2PDE2A | |
| SCHEMBL22201180 | 0.85 | MAPT (0.33) | — | |
| SCHEMBL24286075 | 0.82 | MEN1 (0.32) | KMT2A | |
| SCHEMBL20632928 | 0.82 | KDM4E (0.31) | KDM4EALDH1A1L3MBTL1KMT2A | |
| SCHEMBL22201085 | 0.82 | PPARG (0.31) | PDE2A | |
| SCHEMBL24286076 | 0.81 | TP53 (0.33) | KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL17529564 | 0.81 | CYP1A2 (0.35) | ALDH1A1CYP1A2 | |
| SCHEMBL31476269 | 0.81 | CYP1A2 (0.35) | ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3016949-B1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-13 | — | — | EP | claimed |
| EP-3016949-B1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-13 | — | — | EP | disclosed |