Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 4/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24286075 | 0.87 | MEN1 (0.32) | — | |
| SCHEMBL24286745 | 0.86 | PTGS2 (0.35) | KDM4EALDH1A1PTGS1PTGS2HPGD | |
| SCHEMBL19731192 | 0.83 | LMNA (0.37) | TP53KCNH2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL18179706 | 0.81 | PTGDR2 (0.33) | KDM4EALDH1A1HSD17B10LMNAPTGS1 | |
| SCHEMBL21375974 | 0.81 | MCHR1 (0.32) | PTGS1PTGS2MCHR1 | |
| SCHEMBL21925082 | 0.81 | KDM4E (0.35) | KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL17949389 | 0.81 | KCNH2 (0.41) | KCNH2KDM4EALDH1A1LMNAPTGS1 | |
| SCHEMBL17697064 | 0.80 | PTGS2 (0.35) | KDM4ELMNAPTGS2 | |
| SCHEMBL24286108 | 0.79 | S1PR1 (0.31) | — | |
| SCHEMBL18179701 | 0.79 | PTGS1 (0.32) | LMNAPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247712-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-04-20 | — | — | EP | disclosed |