Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 13/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17432175 | 0.92 | PTGS2 (0.39) | DDR1KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL19439382 | 0.90 | DDR1 (0.38) | DDR1KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL17530254 | 0.90 | GRM5 (0.35) | DDR1KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL21925116 | 0.90 | KDM4E (0.39) | KDM4EALDH1A1CYP1A2HPGDAGPAT2 | |
| SCHEMBL17494853 | 0.89 | DDR1 (0.38) | DDR1PTGDR2AGPAT2CNR2 | |
| SCHEMBL20547541 | 0.88 | CNR2 (0.34) | DDR1KDM4EHPGDCNR2 | |
| SCHEMBL17494868 | 0.88 | DDR1 (0.37) | DDR1ALDH1A1CNR2 | |
| SCHEMBL30958299 | 0.88 | DDR1 (0.37) | DDR1ALDH1A1CNR2 | |
| SCHEMBL17824513 | 0.88 | CA12 (0.36) | KDM4ECNR2 | |
| SCHEMBL30958307 | 0.88 | CNR2 (0.34) | DDR1KDM4EHPGDCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3016949-B1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-13 | — | — | EP | claimed |
| EP-3016949-B1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-13 | — | — | EP | disclosed |