Rilopirox

Rilopirox

SCHEMBL219251

Cc1cc(COc2ccc(Oc3ccc(Cl)cc3)cc2)n(O)c(=O)c1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 17/20 0.69
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9656751 1.00 IDH1 (0.69) IDH1MAPTKDM4ENPC1ALDH1A1
SCHEMBL10726777 0.96 IDH1 (0.74) IDH1MAPTKDM4ENPC1ALDH1A1
SCHEMBL10563264 0.95 IDH1 (0.63) IDH1
SCHEMBL9657972 0.91 IDH1 (0.67) IDH1MAPTKDM4ENPC1ALDH1A1
SCHEMBL9656734 0.91 IDH1 (0.67) IDH1
SCHEMBL14140191 0.90 IDH1 (0.66) IDH1
SCHEMBL9657423 0.89 IDH1 (0.55) IDH1
SCHEMBL9657355 0.89 IDH1 (0.64) IDH1MAPTKDM4ENPC1ALDH1A1
SCHEMBL9656703 0.88 IDH1 (0.54) IDH1
SCHEMBL1856742 0.88 IDH1 (0.60) IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1431 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4149415-B1 SHAMPOO COMPOSITION COMPRISING ALKYL GLUCOSIDE PROCTER & GAMBLE (US) 2026-05-20 EP claimed
EP-4337333-B1 SHAMPOO COMPOSITION PROCTER & GAMBLE (US) 2026-04-15 EP claimed
EP-4698144-A1 PERSONAL CLEANSING COMPOSITION SUBSTANTIALLY FREE OF ALKYL SULFATE OR ALKYL ETHER SULFATE TYPE OF SURFACTANTS The Procter & Gamble Company (US) 2026-02-25 EP claimed
EP-4149416-B1 SHAMPOO COMPOSITION COMPRISING DECYL GLUCOSIDE AND A CATIONIC GUAR PROCTER & GAMBLE (US) 2026-01-21 EP claimed
EP-4676436-A1 PERSONAL CARE COMPOSITION The Procter & Gamble Company (US) 2026-01-14 EP claimed
EP-4676435-A1 PERSONAL CARE COMPOSITION The Procter & Gamble Company (US) 2026-01-14 EP claimed
EP-4637699-A1 SULFATE-FREE DILUTABLE COMPACT PERSONAL CLEANSING COMPOSITION The Procter & Gamble Company (US) 2025-10-29 EP claimed
EP-4637700-A1 DILUTABLE COMPACT PERSONAL CLEANSING COMPOSITION The Procter & Gamble Company (US) 2025-10-29 EP claimed
WO-2025025191-A1 PERSONAL CLEANSING COMPOSITION SUBSTANTIALLY FREE OF ALKYL SULFATE OR ALKYL ETHER SULFATE TYPE OF SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 2025-02-06 WO claimed
US-20250041186-A1 PERSONAL CLEANSING COMPOSITION FREE OF ALKYL SULFATE OR ALKYL ETHER SULFATE TYPE OF SURFACTANTS THE PROCTER & GAMBLE COMPANY 2025-02-06 US claimed
WO-1997020559-A1 USE OF FUNGICIDAL AGENTS FOR SELECTIVE DECONTAMINATION OF TEETH AND DENTAL PROSTHESES HOECHST AKTIENGESELLSCHAFT (DE) 1997-06-12 WO claimed
EP-0777457-A1 USE OF GLYCERYL TRIACETATE FOR TREATING ONYCHOMYCOSES HOECHST AKTIENGESELLSCHAFT (DE) 1997-06-11 EP claimed
WO-1996041626-A1 COMPOSITIONS COMPRISING A CYCLOOXYGENASE-2 INHIBITOR AND A 5-LIPOXYGENASE INHIBITOR G.D. SEARLE & CO. (US) 1996-12-27 WO claimed
WO-1996036311-A1 USE OF GLYCERYL TRIACETATE FOR TREATING ONYCHOMYCOSES HOECHST AKTIENGESELLSCHAFT (DE) 1996-11-21 WO claimed
US-5494658-A CONTAINING A BENZENE AND A 1,2-DIHYDROPYRID-1-OL-2-ONE RINGS HOECHST AKTIENGESELLSCHAFT (DE) 1996-02-27 US claimed
EP-0646369-A1 Cosmetic compositions comprising 1-hydroxy-2-pyridones as antidandruff and deodorant agents HOECHST AKTIENGESELLSCHAFT (DE) 1995-04-05 EP claimed
EP-0634166-A1 Drug compositions containing coated, poorly watersoluble drugs for use in pharmaceutical inhalation forms and method to produce them HOECHST AKTIENGESELLSCHAFT (DE) 1995-01-18 EP claimed
EP-0241918-B1 1-HYDROXY-2-PYRIDINONES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM, AS WELL AS INTERMEDIATES FORMED BY THE PREPARATION OF 1-HYDROXY-2-PYRIDINONES HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-27 EP claimed
US-4797409-A FUNGICIDES, YEAST INFECTIONS HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-10 US claimed
EP-0241918-A2 1-Hydroxy-2-pyridinones, process for their preparation and medicines containing them, as well as intermediates formed by the preparation of 1-hydroxy-2-pyridinones HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-21 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250041186-A1 PERSONAL CLEANSING COMPOSITION FREE OF ALKYL SULFATE OR ALKYL ETHER SULFATE TYPE OF SURFACTANTS STS, ARSA, DEGS1 IDH1 3313/4885MAPT 4237/4885KDM4E 2119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.