Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 12/20 | 0.63 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656734 | 0.96 | IDH1 (0.67) | IDH1MAOAMAOBGRM5NR4A2 | |
| Rilopirox SCHEMBL219251 | 0.95 | IDH1 (0.69) | IDH1 | |
| SCHEMBL9656751 | 0.95 | IDH1 (0.69) | IDH1 | |
| SCHEMBL10726777 | 0.91 | IDH1 (0.74) | IDH1 | |
| SCHEMBL14140191 | 0.90 | IDH1 (0.66) | IDH1 | |
| SCHEMBL9657992 | 0.88 | IDH1 (0.67) | IDH1MAOAMAOBGRM5NR4A2 | |
| SCHEMBL9657972 | 0.86 | IDH1 (0.67) | IDH1 | |
| SCHEMBL20283822 | 0.85 | IDH1 (0.51) | IDH1MAOAMAOBGRM5NR4A2 | |
| SCHEMBL9657423 | 0.85 | IDH1 (0.55) | IDH1 | |
| SCHEMBL9657355 | 0.84 | IDH1 (0.64) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4797409-A | FUNGICIDES, YEAST INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | disclosed |