Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL16026754 | 0.94 | — | — | |
| Bicarbonate SCHEMBL48350 | 0.93 | — | — | |
| Bicarbonate SCHEMBL27913252 | 0.93 | — | — | |
| Bicarbonate SCHEMBL27527 | 0.93 | — | — | |
| Bicarbonate SCHEMBL28459165 | 0.93 | — | — | |
| Bicarbonate SCHEMBL20913735 | 0.86 | CA1 (0.71) | — | |
| Bicarbonate SCHEMBL6691298 | 0.86 | CA1 (0.71) | — | |
| Bicarbonate SCHEMBL21056252 | 0.86 | — | — | |
| Bicarbonate SCHEMBL21056250 | 0.86 | — | — | |
| Bicarbonate SCHEMBL372447 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3648883-A1 | SYSTEM CONSISTING OF A SUBSTRATE WITH FLOW CHANNELS AND A WASH-COAT-FREE CATALYTIC COATING | Exentis Knowledge GmbH (CH) | 2020-05-13 | — | — | EP | disclosed |