Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21924038 | 0.80 | — | — | |
| SCHEMBL21281476 | 0.78 | DDB1 (0.30) | DDB1CRBN | |
| SCHEMBL23938908 | 0.76 | — | — | |
| SCHEMBL20459245 | 0.70 | DDB1 (0.36) | DDB1CRBN | |
| SCHEMBL23939063 | 0.65 | — | — | |
| SCHEMBL23938887 | 0.65 | — | — | |
| SCHEMBL21281361 | 0.64 | — | — | |
| SCHEMBL23939049 | 0.60 | CRBN (0.35) | DDB1CRBN | |
| SCHEMBL23939274 | 0.60 | DDB1 (0.35) | DDB1CRBN | |
| SCHEMBL25031787 | 0.59 | CRBN (0.54) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643709-A1 | ISOINDOLINE DERIVATIVE, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Kangpu Biopharmaceuticals, Ltd. (CN) | 2020-04-29 | — | — | EP | disclosed |