⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30696109 | 0.98 | — | — | |
| SCHEMBL30874385 | 0.98 | — | — | |
| SCHEMBL2592585 | 0.65 | — | — | |
| SCHEMBL28829629 | 0.65 | — | — | |
| SCHEMBL2387226 | 0.65 | — | — | |
| SCHEMBL19163803 | 0.61 | — | — | |
| SCHEMBL3313260 | 0.61 | — | — | |
| Water SCHEMBL30136134 | 0.59 | — | — | |
| SCHEMBL2353333 | 0.59 | — | — | |
| SCHEMBL7945578 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122074043-A | Combination therapy with KRAS modulators | 光达治疗公司 | 2026-05-22 | — | — | CN | claimed |
| US-12606744-B2 | Zinc pigment for waterborne corrosion coatings | SUN CHEMICAL CORPORATION (US) | 2026-04-21 | — | — | US | claimed |
| US-20250223285-A1 | NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS | JACOBIO PHARMACEUTICALS CO LTD (CN) | 2025-07-10 | — | — | US | claimed |
| CN-119977981-A | Dihydrofuran fused hetero pyrrolizine derivatives, and preparation method and application thereof | 天津科技大学 | 2025-05-13 | — | — | CN | claimed |
| WO-2025096738-A1 | KRAS INHIBITORS | INCYTE CORPORATION (US) | 2025-05-08 | — | — | WO | claimed |
| CN-115746001-B | Preparation method of chiral pyrrolizine-3-ketone compound | 浙江工业大学 | 2025-04-29 | — | — | CN | claimed |
| CN-116568764-B | Zinc pigments for aqueous anticorrosive coatings | 太阳化学公司 | 2025-04-11 | — | — | CN | claimed |
| WO-2025034919-A1 | COMBINATION THERAPIES WITH KRAS MODULATORS | QUANTA THERAPEUTICS, INC. (US) | 2025-02-13 | — | — | WO | claimed |
| WO-2025034883-A1 | COMBINATION THERAPIES WITH KRAS MODULATORS | QUANTA THERAPEUTICS, INC. (US) | 2025-02-13 | — | — | WO | claimed |
| EP-4475956-A1 | KRAS MODULATORS AND USES THEREOF | Quanta Therapeutics, Inc. (US) | 2024-12-18 | — | — | EP | claimed |
| CN-112062799-B | Methoxy-substituted arabinose triazole structure spiroisoxazole-pyrrolizine derivative and preparation method and application thereof | 绍兴文理学院元培学院 | 2022-05-06 | — | — | CN | claimed |
| WO-2022079246-A1 | NLRP3 ACTIVATORS FOR USE IN THE TREATMENT OF INFECTIOUS DISEASES OR CANCER BY ACTIVATING NLRP3 INFLAMMASOME | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2022-04-21 | — | — | WO | claimed |
| EP-3984535-A1 | NLRP3 ACTIVATORS FOR USE IN THE TREATMENT OF INFECTIOUS DISEASES OR CANCER BY ACTIVATING NLRP3 INFLAMMASOME | Albert-Ludwigs-Universität Freiburg (DE) | 2022-04-20 | — | — | EP | claimed |
| CN-112881581-B | Method for quantitatively detecting pyrrolin and methyl glyoxal hydrogen imidazolone in aquatic product | 中国海洋大学 | 2022-04-01 | — | — | CN | claimed |
| CN-109223779-B | Pharmaceutical composition for promoting fracture healing and preparation method and application thereof | 山东中医药大学 | 2020-07-17 | — | — | CN | claimed |
| US-8492538-B1 | Cyclodextrin derivative salts | MATOS JOSE R (US) | 2013-07-23 | — | — | US | claimed |
| EP-0889718-B1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING PYRROLO-AZOLE COMPOUNDS, USE THEREOF AS COUPLERS, AND DYEING METHOD | OREAL (FR) | 2002-09-18 | — | — | EP | claimed |
| US-20010020309-A1 | Compositions for dyeing keratinous fibres, containing pyrrolo-azoles; use as couplers; method of dyeing | L'OREAL S.A. | 2001-09-13 | — | — | US | claimed |
| US-6238440-B1 | OXIDATION-DYEING HAIR | L'OREAL S.A. (FR) | 2001-05-29 | — | — | US | claimed |
| EP-0041711-B1 | 6-CHLORO- OR 6-BROMO-1,2-DIHYDRO-3H-PYRROLO(1,2-A)-PYRROLE-1-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYNTEX (U.S.A.) INC. (US) | 1985-04-17 | — | — | EP | claimed |