⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2192806 | 0.65 | — | — | |
| SCHEMBL11769351 | 0.65 | ALOX5 (0.32) | — | |
| SCHEMBL1692539 | 0.64 | — | — | |
| SCHEMBL30696109 | 0.64 | — | — | |
| SCHEMBL30874385 | 0.64 | — | — | |
| SCHEMBL2387226 | 0.61 | — | — | |
| SCHEMBL28829629 | 0.61 | — | — | |
| SCHEMBL6264007 | 0.58 | — | — | |
| SCHEMBL208858 | 0.55 | — | — | |
| SCHEMBL2353333 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023173016-A1 | KRAS INHIBITORS FOR TREATING DISEASE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | WO | claimed |
| EP-4618975-A2 | INHIBITORS OF TYK2 | Vyrnwy Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107658-A2 | INHIBITORS OF TYK2 | VYRNWY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| CN-117836297-A | (S) -1- (5- ((pyridin-3-yl) thio) pyrazin-2-yl) -4'H,6' H-spiro [ piperidine-4, 5 '-pyrrolo [1,2-B ] pyrazol ] -4' -amine derivatives and similar compounds as SHP2 inhibitors for the treatment of, for example, cancer | 国家化学成分收集和筛选中心 | 2024-04-05 | — | — | CN | disclosed |
| CN-117069725-A | Imidazopyridazine substituted benzene ring derivative, preparation method, pharmaceutical composition and application | 上海赛默罗生物科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| WO-2023173016-A1 | KRAS INHIBITORS FOR TREATING DISEASE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | WO | disclosed |
| CN-114907389-A | Boronic acid derivatives | 首药控股(北京)股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-102292333-B | Protein kinase c inhibitors and uses thereof | RIGEL PHARMACEUTICALS INC | 2015-05-13 | — | — | CN | disclosed |
| EP-2595989-A1 | HETEROCYCLIC CHROMENE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS | Vertex Pharmaceuticals Incorporated (US) | 2013-05-29 | — | — | EP | disclosed |
| CN-102292333-A | Protein kinase c inhibitors and uses thereof | — | 2011-12-21 | — | — | CN | disclosed |
| WO-2003035073-A1 | ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | ASTRAZENECA AB (SE) | 2003-05-01 | — | — | WO | disclosed |
| WO-2002080841-A2 | ANTIBACTERIAL OXAZOLIDINONES WITH A CYCLIC SULPHILIMINE OR SULPHOXIMINE | ASTRAZENECA AB (SE) | 2002-10-17 | — | — | WO | disclosed |
| WO-2002081470-A1 | OXAZOLIDINONES CONTAINING A SULFONIMID GROUP AS ANTIBIOTICS | ASTRAZENECA AB (SE) | 2002-10-17 | — | — | WO | disclosed |
| WO-2002081469-A1 | OXAZOLIDINONE-SULFOXIMINES AND -SULFILIMINES AS ANTIBIOTICS | ASTRAZENECA AB (SE) | 2002-10-17 | — | — | WO | disclosed |
| CN-1311787-A | oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them | ASTRA ZENECA CO LTD (SE) | 2001-09-05 | — | — | CN | disclosed |
| EP-1121358-A1 | HETEROCYCLYLAMINOMETHYLOXAZOLIDINONES AS ANTIBACTERIALS | AstraZeneca AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| CN-1304410-A | Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them | ASTRA ZENECA LTD (SE) | 2001-07-18 | — | — | CN | disclosed |
| EP-1082322-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AstraZeneca AB (SE) | 2001-03-14 | — | — | EP | disclosed |
| WO-2000021960-A1 | HETEROCYCLYL AMINO METHYLOXA ZOLIDINONES AS ANTIBACTERIALS | ASTRAZENECA AB (SE) | 2000-04-20 | — | — | WO | disclosed |
| WO-1999064416-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 1999-12-16 | — | — | WO | disclosed |