Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.79 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17919752 | 0.85 | KDM2B (1.00) | L3MBTL1KDM2BKDM4EMEN1KMT2A | |
| SCHEMBL17919629 | 0.85 | KDM2B (1.00) | L3MBTL1KDM2BKDM4EMEN1KMT2A | |
| SCHEMBL19798980 | 0.85 | KDM2B (1.00) | L3MBTL1KDM2BKDM4EMEN1KMT2A | |
| SCHEMBL29576567 | 0.85 | KDM2B (1.00) | L3MBTL1KDM2BKDM4EMEN1KMT2A | |
| SCHEMBL21926832 | 0.84 | KDM2B (0.73) | L3MBTL1KDM2BKDM4EMEN1KMT2A | |
| SCHEMBL21926438 | 0.83 | ALDH1A1 (0.74) | KDM2BKDM4EMEN1KMT2APOLB | |
| SCHEMBL21926939 | 0.81 | KDM2B (0.69) | L3MBTL1KDM2BKDM4EMEN1KMT2A | |
| SCHEMBL29333202 | 0.80 | KDM4E (0.67) | L3MBTL1KDM4EMEN1KMT2ACYP2D6 | |
| SCHEMBL8350398 | 0.80 | CYP3A4 (0.83) | KDM2BKDM4EMEN1KMT2APOLB | |
| SCHEMBL21926824 | 0.80 | CYP3A4 (0.74) | L3MBTL1KDM2BKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131125-A1 | ARYL-PIPERIDINE DERIVATIVES | ARTAX BIOPHARMA INC. | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131125-A1 | ARYL-PIPERIDINE DERIVATIVES | CD4, CD2, CCR1 | L3MBTL1 2526/4885KDM2B 424/4885KDM4E 497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.