SCHEMBL2193200

SCHEMBL2193200

CC(C)C[C@@H]([C]=O)NC(=O)[C@@H](N)CC(C)C

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.45
LARS1 Q9P2J5 3/20 0.40
SCN9A Q15858 4/20 0.39
ANPEP P15144 3/20 0.39
RNPEP Q9H4A4 2/20 0.39
DNPEP Q9ULA0 2/20 0.39
AAK1 Q2M2I8 1/20 0.38
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36
CTSC P53634 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29010766 1.00 SLC7A5 (0.45) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL21625553 1.00 SLC7A5 (0.45) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL29010817 1.00 SLC7A5 (0.45) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL7318989 1.00 SLC7A5 (0.45) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL8863575 0.93 SLC7A5 (0.40) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL1795666 0.93 SLC7A5 (0.40) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL28082201 0.92 MMP2 (0.39) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL2184616 0.92 MMP2 (0.39) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL3498456 0.90 SLC7A5 (0.40) SLC7A5LARS1SCN9ASLC1A3SLC1A2
SCHEMBL6141906 0.90 DPP4 (0.36) SLC7A5LARS1SCN9AANPEPRNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230381267-A1 OXYTOCIN TREATMENT FOR HYPERMOBILE EHLERS-DANLOS SYNDROME BAYLOR COLLEGE OF MEDICINE 2023-11-30 US claimed
EP-4221834-A1 OXYTOCIN TREATMENT FOR HYPERMOBILE EHLERS-DANLOS SYNDROME Baylor College of Medicine (US) 2023-08-09 EP claimed
CN-1658819-A Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form OREAL (FR) 2005-08-24 CN claimed
EP-1515684-A2 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM L'OREAL (FR) 2005-03-23 EP claimed
WO-2003105788-A2 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM L'OREAL (FR) 2003-12-24 WO claimed
US-6468977-B1 COMPOUNDS USEFUL IN TREATMENT TREATMENT OF DISORDER AND/OR DISEASE CAUSED BY ACTIVITY OF ENZYMES SUCH AS HUMAN RHINOVIRUS 3C PROTEASE, TRANSGLUTAMINASE AND CATHEPSINS APOTEX INC. (CA) 2002-10-22 US claimed
EP-0272671-B1 Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors SANDOZ LTD (CH) 1994-03-16 EP claimed
US-5055451-A Prevent tissue damage SYNTEX INC. (US) 1991-10-08 US claimed
EP-0272671-A2 Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors SANDOZ LTD. (CH) 1988-06-29 EP claimed
US-20230381267-A1 OXYTOCIN TREATMENT FOR HYPERMOBILE EHLERS-DANLOS SYNDROME BAYLOR COLLEGE OF MEDICINE 2023-11-30 US disclosed
EP-4221834-A1 OXYTOCIN TREATMENT FOR HYPERMOBILE EHLERS-DANLOS SYNDROME Baylor College of Medicine (US) 2023-08-09 EP disclosed
CN-109879933-B Phosphoryl-containing compound and application thereof 河北科技大学 2023-06-06 CN disclosed
CN-109796519-B Steroid compound and application thereof 河北科技大学 2023-01-10 CN disclosed
WO-2021030267-A1 COMPOSITIONS AND METHODS FOR INCREASED PROTEIN PRODUCTION IN BACILLUS LICHENIFORMIS DANISCO US INC (US) 2021-02-18 WO disclosed
US-5158936-A Treating or prevention of tissue damage, inflammation, bone resporpption and muscular dystrophy SYNTEX (U.S.A.) INC. (US) 1992-10-27 US disclosed
US-5055451-A Prevent tissue damage SYNTEX INC. (US) 1991-10-08 US disclosed
EP-0272671-A2 Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors SANDOZ LTD. (CH) 1988-06-29 EP disclosed
EP-0010297-B1 DERIVATIVES OF POLYENE MACROLIDE ANTIBIOTICS CONTAINING AN AMINO SUGAR MOIETY, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SCHERING CORPORATION (US) 1983-04-13 EP disclosed
US-4272525-A FUNGICIDES SCHERING CORPORATION (US) 1981-06-09 US disclosed
EP-0010297-A1 Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them SCHERING CORPORATION (US) 1980-04-30 EP disclosed