Fluoride

Fluoride

SCHEMBL21933484

CC1COC(C)(C(=O)O)O1.F

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.34
LMNA P02545 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
TP53 P04637 1/20 0.34
NFKB1 P19838 1/20 0.34
CYP2C19 P33261 1/20 0.34
THPO P40225 1/20 0.34
STAT6 P42226 1/20 0.34
HIF1A Q16665 1/20 0.34
NPC1 O15118 1/20 0.34
GMNN O75496 1/20 0.34
MTOR P42345 1/20 0.34
RAB9A P51151 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
FFAR3 O14843 1/20 0.32
PPARA Q07869 4/20 0.31
PPARG P37231 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL22129962 0.98 MAPK1 (0.33) MAPK1LMNASMN1; SMN2TP53NFKB1
Fluoride SCHEMBL23795544 0.98 MAPK1 (0.33) MAPK1LMNASMN1; SMN2TP53NFKB1
Fluoride SCHEMBL23795550 0.98 MAPK1 (0.33) MAPK1LMNASMN1; SMN2TP53NFKB1
SCHEMBL16796676 0.98 MAPK1 (0.35) MAPK1LMNASMN1; SMN2TP53NFKB1
SCHEMBL28678942 0.96 MAPK1 (0.34) MAPK1LMNASMN1; SMN2TP53NFKB1
SCHEMBL28596043 0.96 MAPK1 (0.34) MAPK1LMNASMN1; SMN2TP53NFKB1
SCHEMBL20581981 0.83 MAPK1 (0.36) MAPK1LMNASMN1; SMN2TP53NFKB1
SCHEMBL20054634 0.83 MAPK1 (0.36) MAPK1LMNASMN1; SMN2TP53NFKB1
SCHEMBL22127645 0.83 MAPK1 (0.36) MAPK1LMNASMN1; SMN2TP53NFKB1
SCHEMBL20054632 0.83 MAPK1 (0.36) MAPK1LMNASMN1; SMN2TP53NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3878845-B1 PERFLUORO(2-METHYLENE-4-METHYL-1,3-DIOXOLANE) PRODUCTION METHOD TOSOH CORP (JP) 2023-06-21 EP claimed
US-20220002262-A1 METHOD OF PRODUCING PERFLUORO(2-METHYLENE-4-METHYL-1,3-DIOXOLANE) TOSOH CORPORATION (JP) 2022-01-06 US claimed
EP-3878845-A1 PERFLUORO(2-METHYLENE-4-METHYL-1,3-DIOXOLANE) PRODUCTION METHOD Tosoh Corporation (JP) 2021-09-15 EP claimed
US-20250382275-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING DIOXOLANE, AND COMPOSITION USEFUL FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2025-12-18 US disclosed
EP-3878845-B1 PERFLUORO(2-METHYLENE-4-METHYL-1,3-DIOXOLANE) PRODUCTION METHOD TOSOH CORP (JP) 2023-06-21 EP disclosed
WO-2023033073-A1 PRODUCTION METHOD FOR FLUORINE-CONTAINING DIOXOLANE AND COMPOSITION USEFUL FOR PRODUCTION OF SAME ダイキン工業株式会社 2023-03-09 WO disclosed
US-20220002262-A1 METHOD OF PRODUCING PERFLUORO(2-METHYLENE-4-METHYL-1,3-DIOXOLANE) TOSOH CORPORATION (JP) 2022-01-06 US disclosed
US-20220002262-A1 METHOD OF PRODUCING PERFLUORO(2-METHYLENE-4-METHYL-1,3-DIOXOLANE) TOSOH CORPORATION (JP) 2022-01-06 US disclosed
EP-3878845-A1 PERFLUORO(2-METHYLENE-4-METHYL-1,3-DIOXOLANE) PRODUCTION METHOD Tosoh Corporation (JP) 2021-09-15 EP disclosed
EP-3878845-A1 PERFLUORO(2-METHYLENE-4-METHYL-1,3-DIOXOLANE) PRODUCTION METHOD Tosoh Corporation (JP) 2021-09-15 EP disclosed
WO-2020095915-A1 PERFLUORO(2-METHYLENE-4-METHYL-1,3-DIOXOLANE) PRODUCTION METHOD 東ソ-株式会社 2020-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220002262-A1 METHOD OF PRODUCING PERFLUORO(2-METHYLENE-4-METHYL-1,3-DIOXOLANE) AFF1, AFF2, AFF4 MAPK1 2332/4885LMNA 1121/4885SMN1; SMN2 1697/4885
US-20250382275-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING DIOXOLANE, AND COMPOSITION USEFUL FOR PRODUCING SAME AFF1, HAO2, F9 MAPK1 1301/4885LMNA 531/4885SMN1; SMN2 1597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.