Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20806065 | 0.83 | CYP1A1 (0.41) | ESR1ESR2 | |
| SCHEMBL20806198 | 0.81 | ESR1 (0.37) | ESR1ESR2STSHSD17B1HSD17B2 | |
| SCHEMBL16265236 | 0.80 | ESR1 (0.38) | ESR1ESR2 | |
| SCHEMBL26500096 | 0.77 | HSD17B1 (0.42) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL16265225 | 0.76 | ESR1 (0.33) | ESR1ESR2ALOX5APFEN1 | |
| SCHEMBL19369162 | 0.75 | ESR2 (0.46) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL19682268 | 0.75 | APP (0.41) | ESR1ESR2 | |
| SCHEMBL16265326 | 0.74 | AHR (0.38) | — | |
| SCHEMBL20806237 | 0.74 | ESR2 (0.45) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL20806196 | 0.73 | ESR1 (0.31) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3400270-B1 | DEVICE FOR REGULATING ENTRY OF LIGHT | MERCK PATENT GMBH (DE) | 2020-04-29 | — | — | EP | disclosed |