Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 8/20 | 0.64 |
| ▸ | CCNC | P24863 | 3/20 | 0.49 |
| ▸ | CDK8 | P49336 | 3/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21935670 | 0.90 | CHRM1 (0.71) | CHRM1 | |
| SCHEMBL6890837 | 0.88 | CHRM1 (0.69) | CHRM1CCNCCDK8BRD4 | |
| SCHEMBL21873543 | 0.88 | CHRM1 (0.55) | CHRM1 | |
| SCHEMBL31669000 | 0.88 | CHRM1 (0.55) | CHRM1 | |
| SCHEMBL31668947 | 0.88 | CHRM1 (0.63) | CHRM1 | |
| SCHEMBL21873405 | 0.88 | CHRM1 (0.63) | CHRM1 | |
| SCHEMBL21935669 | 0.88 | CHRM1 (0.64) | CHRM1CCNCCDK8BRD4WNT1 | |
| SCHEMBL21935759 | 0.87 | CHRM1 (0.55) | CHRM1BRD4 | |
| SCHEMBL23673084 | 0.84 | CHRM1 (0.64) | CHRM1CCNCCDK8BRD4WNT1 | |
| SCHEMBL21873507 | 0.83 | PIM1 (0.45) | CHRM1CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643718-B1 | HETEROCYCLIC COMPOUND AND ITS USE AS POSITIVE ALLOSTERIC MODULATOR OF THE CHOLINERGIC MUSCARINIC M1 RECEPTOR. | TAKEDA PHARMACEUTICALS CO (JP) | 2023-07-26 | — | — | EP | disclosed |
| EP-3643718-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-04-29 | — | — | EP | disclosed |