Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 11/20 | 0.69 |
| ▸ | CCNC | P24863 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6889896 | 0.90 | CHRM1 (0.78) | CHRM1BRD4 | |
| SCHEMBL21935401 | 0.88 | CHRM1 (0.64) | CHRM1CCNCCDK8BRD4 | |
| SCHEMBL2226588 | 0.88 | CHRM1 (0.74) | CHRM1 | |
| SCHEMBL21935669 | 0.86 | CHRM1 (0.64) | CHRM1CCNCCDK8BRD4 | |
| SCHEMBL23673084 | 0.86 | CHRM1 (0.64) | CHRM1CCNCCDK8BRD4 | |
| SCHEMBL16948147 | 0.84 | CHRM1 (0.78) | CHRM1CCNCCDK8 | |
| SCHEMBL21935357 | 0.83 | CHRM1 (0.64) | CHRM1CCNCCDK8BRD4 | |
| SCHEMBL21859103 | 0.81 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL6891034 | 0.81 | CHRM1 (0.65) | CHRM1CCNCCDK8 | |
| SCHEMBL17656776 | 0.81 | CHRM1 (0.65) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084368-A1 | QUINOLINE AMIDE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2011-07-14 | — | — | WO | disclosed |