Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | CCR8 | P51685 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21933841 | 1.00 | PIK3CA (0.39) | PIK3CAMETAP1KDM4EMAPK1CCR1 | |
| SCHEMBL21934328 | 1.00 | PIK3CA (0.39) | PIK3CAMETAP1KDM4EMAPK1CCR1 | |
| SCHEMBL21934210 | 1.00 | PIK3CA (0.39) | PIK3CAMETAP1KDM4EMAPK1CCR1 | |
| SCHEMBL21934860 | 0.99 | PIK3CA (0.38) | PIK3CAMETAP1KDM4EMAPK1CCR1 | |
| SCHEMBL21934326 | 0.99 | PIK3CA (0.38) | PIK3CAMETAP1KDM4EMAPK1CCR1 | |
| SCHEMBL21935708 | 0.98 | METAP1 (0.38) | PIK3CAMETAP1KDM4EMAPK1CCR1 | |
| SCHEMBL21934866 | 0.97 | METAP1 (0.37) | PIK3CAMETAP1KDM4EMAPK1CCR1 | |
| SCHEMBL21933861 | 0.97 | PIK3CA (0.38) | PIK3CAMETAP1KDM4EMAPK1CCR1 | |
| SCHEMBL21933831 | 0.96 | PIK3CA (0.46) | PIK3CAMETAP1KDM4EMAPK1CCR1 | |
| SCHEMBL21934343 | 0.95 | PIK3CA (0.39) | PIK3CAMETAP1KDM4EMAPK1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131133-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | HEESUNG MATERIAL LTD. (KR) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131133-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | CRY1, CYP1A1, CYP1B1 | PIK3CA 4341/4885METAP1 2919/4885KDM4E 2576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.