SCHEMBL21936045

SCHEMBL21936045

CC[S+]([O-])c1ccc(CN)nc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 0.30
WDR77 Q9BQA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21299509 0.76
SCHEMBL20482192 0.74 MAPT (0.41)
SCHEMBL17674414 0.72 PRMT5 (0.34) PRMT5WDR77
SCHEMBL18477987 0.71 PSIP1 (0.45)
SCHEMBL15231964 0.70
SCHEMBL20482185 0.67
SCHEMBL2600004 0.67 HRH3 (0.50)
SCHEMBL23021460 0.66 NPC1 (0.42)
SCHEMBL1631010 0.66
SCHEMBL20226629 0.66 GAA (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020082921-A1 NITROGEN HETEROARYL AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 上海和誉生物医药科技有限公司 2020-04-30 WO disclosed