Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 15/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 14/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 14/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 14/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 13/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22548632 | 0.77 | CCR5 (0.35) | CCR5CHRNA4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2386258 | 0.74 | CHRNA4 (0.43) | BPTFCCR5CHRNA4CHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL20483822 | 0.72 | CHRNA4 (0.41) | BPTFCCR5CHRNA4CHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL29663909 | 0.72 | CHRNA4 (0.41) | BPTFCCR5CHRNA4CHRNB2CHRNB4 | |
| SCHEMBL20858712 | 0.68 | — | — | |
| SCHEMBL18685427 | 0.68 | CHRNA7 (0.30) | CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL16129116 | 0.67 | CHRNA4 (0.38) | BPTFCCR5CHRNA4CHRNB2CHRNB4 | |
| SCHEMBL1463765 | 0.66 | CHRNA4 (0.55) | CHRNA4CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL18887698 | 0.64 | — | — | |
| SCHEMBL21216455 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381896-B1 | BIPHENYL COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2023-01-18 | — | — | EP | disclosed |
| EP-3633380-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFECT OF LSD1 INHIBITOR BASED ON EXPRESSION OF INSM1 | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-04-08 | — | — | EP | disclosed |