Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 17/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30428011 | 0.89 | CHRM1 (0.67) | CHRM1 | |
| SCHEMBL21873485 | 0.89 | CHRM1 (0.67) | CHRM1 | |
| SCHEMBL21873386 | 0.85 | CHRM1 (0.64) | CHRM1 | |
| SCHEMBL31668938 | 0.85 | CHRM1 (0.64) | CHRM1 | |
| SCHEMBL31668963 | 0.84 | CHRM1 (0.72) | CHRM1 | |
| SCHEMBL21873399 | 0.84 | CHRM1 (0.72) | CHRM1 | |
| SCHEMBL23673082 | 0.83 | CHRM1 (0.52) | CHRM1 | |
| SCHEMBL21873503 | 0.83 | MPO (0.44) | CHRM1 | |
| SCHEMBL30428202 | 0.83 | MPO (0.44) | CHRM1 | |
| SCHEMBL21235339 | 0.82 | CHRM1 (0.61) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643718-B1 | HETEROCYCLIC COMPOUND AND ITS USE AS POSITIVE ALLOSTERIC MODULATOR OF THE CHOLINERGIC MUSCARINIC M1 RECEPTOR. | TAKEDA PHARMACEUTICALS CO (JP) | 2023-07-26 | — | — | EP | disclosed |
| EP-3643718-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-04-29 | — | — | EP | disclosed |