Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | CD44 | P16070 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14547572 | 0.82 | HTR2C (0.32) | HTR2CCD44CYP1A2CYP2A6 | |
| SCHEMBL21009663 | 0.80 | MAP3K14 (0.34) | HTR2CCD44CYP1A2CYP2A6 | |
| SCHEMBL423294 | 0.80 | ADORA2A (0.35) | HTR2CCD44CYP1A2CYP2A6 | |
| SCHEMBL7693244 | 0.80 | HTR2C (0.33) | HTR2CCD44CYP1A2CYP2A6 | |
| SCHEMBL14747859 | 0.77 | HTR2C (0.31) | HTR2CCD44CYP1A2CYP2A6 | |
| SCHEMBL9058839 | 0.76 | HTR2C (0.30) | HTR2C | |
| SCHEMBL10522329 | 0.74 | ALDH1A1 (0.46) | HTR2CCD44CYP1A2CYP2A6 | |
| SCHEMBL7267859 | 0.72 | MAP3K14 (0.34) | HTR2CCD44CYP1A2CYP2A6 | |
| SCHEMBL25121118 | 0.71 | CD44 (0.35) | HTR2CCD44CYP1A2CYP2A6 | |
| SCHEMBL9776180 | 0.69 | CNR1 (0.32) | HTR2CCD44CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636639-A1 | INHIBITORS OF KRAS G12C | Araxes Pharma LLC (US) | 2020-04-15 | — | — | EP | disclosed |