Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 15/20 | 0.76 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.76 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | TMIGD3 | P0DMS9 | 5/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22359584 | 0.91 | ADORA3 (0.75) | ADORA3ADORA2AADORA1SLC6A3SLC6A2 | |
| SCHEMBL23097510 | 0.91 | ADORA3 (0.75) | ADORA3ADORA2AADORA1SLC6A3SLC6A2 | |
| SCHEMBL20122133 | 0.91 | ADORA3 (0.75) | ADORA3ADORA2AADORA1SLC6A3SLC6A2 | |
| SCHEMBL23097496 | 0.91 | ADORA3 (0.75) | ADORA3ADORA2AADORA1SLC6A3SLC6A2 | |
| SCHEMBL21939668 | 0.87 | ADORA3 (0.75) | ADORA3ADORA2ASLC6A3SLC6A2KCNH2 | |
| SCHEMBL21939669 | 0.86 | ADORA3 (0.71) | ADORA3 | |
| SCHEMBL24615124 | 0.86 | ADORA3 (1.00) | ADORA3ADORA2AADORA1SLC6A3SLC6A2 | |
| SCHEMBL24615068 | 0.86 | ADORA3 (1.00) | ADORA3ADORA2AADORA1SLC6A3SLC6A2 | |
| SCHEMBL24615115 | 0.86 | ADORA3 (1.00) | ADORA3ADORA2AADORA1SLC6A3SLC6A2 | |
| SCHEMBL21779301 | 0.86 | ADORA3 (1.00) | ADORA3ADORA2AADORA1SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020061211-A1 | USE OF HIGHLY-SELECTIVE ADENOSINE 3A RECEPTOR SUBTYPE AGONISTS | SAINT LOUIS UNIVERSITY (US) | 2020-03-26 | — | — | WO | disclosed |