SCHEMBL219397

SCHEMBL219397

NNc1cc2ccccc2cc1NN

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
CYP3A4 P08684 4/20 0.42
HSD17B10 Q99714 2/20 0.42
TDP1 Q9NUW8 4/20 0.41
CYP1A2 P05177 3/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
LMNA P02545 1/20 0.41
IDO1 P14902 1/20 0.41
PTGS2 P35354 1/20 0.41
ALOX15 P16050 1/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
HBB P68871 1/20 0.40
HIF1A Q16665 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA6 P23280 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14320079 0.85 IDO1 (0.42) ALDH1A1CYP3A4HSD17B10TDP1CYP1A2
SCHEMBL6626220 0.78 ALDH1A1 (0.58) ALDH1A1CYP3A4HSD17B10TDP1CYP1A2
SCHEMBL6626253 0.76 ALDH1A1 (0.59) ALDH1A1CYP3A4HSD17B10TDP1CYP1A2
SCHEMBL15845644 0.74 TLR8 (0.56) ALDH1A1HSD17B10LMNAIDO1POLB
SCHEMBL31484713 0.74 ALDH1A1 (0.52) ALDH1A1CYP3A4HSD17B10TDP1CYP1A2
SCHEMBL1537798 0.74 ALDH1A1 (0.52) ALDH1A1CYP3A4HSD17B10TDP1CYP1A2
SCHEMBL24508233 0.71 MEN1 (0.44) ALDH1A1HSD17B10TDP1IDO1POLB
SCHEMBL10829034 0.71 TDP1 (0.44) ALDH1A1HSD17B10TDP1CYP1A2IDO1
SCHEMBL316073 0.70 KDM4E (0.57) ALDH1A1CYP3A4HSD17B10TDP1CYP1A2
SCHEMBL31295286 0.70 ALDH1A1 (0.58) ALDH1A1CYP3A4HSD17B10TDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2246403-A1 Waterborne adhesive formulations Akzo Nobel Coatings International B.V. (NL) 2010-11-03 EP claimed
EP-4377368-B1 AQUEOUS POLYURETHANE DISPERSION ALLNEX AUSTRIA GMBH (AT) 2025-06-18 EP disclosed
US-20240425630-A1 POLYMER DISPERSION COMPOSITION DOW GLOBAL TECHNOLOGIES LLC (US) 2024-12-26 US disclosed
US-20240352178-A1 AQUEOUS POLYURETHANE DISPERSION ALLNEX AUSTRIA GMBH (AT) 2024-10-24 US disclosed
EP-4448590-A1 POLYMER DISPERSION COMPOSITION Dow Global Technologies LLC (US) 2024-10-23 EP disclosed
EP-4400523-A1 AQUEOUS POLYURETHANE-VINYL POLYMER HYBRID DISPERSION Allnex Austria GmbH (AT) 2024-07-17 EP disclosed
EP-4377368-A1 AQUEOUS POLYURETHANE DISPERSION Allnex Austria GmbH (AT) 2024-06-05 EP disclosed
CN-117642443-A Aqueous polyurethane dispersions 湛新奥地利有限公司 2024-03-01 CN disclosed
WO-2023114625-A1 POLYMER DISPERSION COMPOSITION DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-22 WO disclosed
WO-2023006502-A1 AQUEOUS POLYURETHANE DISPERSION ALLNEX AUSTRIA GMBH (AT) 2023-02-02 WO disclosed
EP-0332326-B1 POLYURETHANE COATING COMPOSITIONS ICI RESINS BV (NL) 1993-03-03 EP disclosed
US-4988762-A Crosslinking coating comprising aziridine-modified addition polymers having pendant ketones or aldehydes; protective coatings; adhesives; imination ICI RESINS B.V. (NL) 1991-01-29 US disclosed
US-4983662-A SELF-CROSSLINKING THROUGH HYDRAZINE OR HYDRAZONE AND CARBONYL FUNCTIONAL GROUPS ICI RESINS B.V. (NL) 1991-01-08 US disclosed
EP-0341886-A2 Aqueous coating compositions ZENECA RESINS BV (NL) 1989-11-15 EP disclosed
EP-0332326-A2 Polyurethane coating compositions ICI RESINS BV (NL) 1989-09-13 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
US-4250070-A ALSO CONTAINING HEAVY METAL IONS; STORAGE STABILITY; CROSSLINKING; COATINGS BASF AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed