Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL323394 | 1.00 | — | — | |
| SCHEMBL19689400 | 1.00 | HDAC4 (0.34) | HDAC4HDAC2HDAC8HDAC6TRPA1 | |
| SCHEMBL17653495 | 1.00 | HDAC4 (0.34) | HDAC4HDAC2HDAC8HDAC6TRPA1 | |
| SCHEMBL31016738 | 1.00 | HDAC4 (0.34) | HDAC4HDAC2HDAC8HDAC6TRPA1 | |
| SCHEMBL4578692 | 1.00 | HDAC4 (0.34) | HDAC4HDAC2HDAC8HDAC6TRPA1 | |
| SCHEMBL11952530 | 1.00 | HDAC4 (0.34) | HDAC4HDAC2HDAC8HDAC6TRPA1 | |
| SCHEMBL17653494 | 1.00 | HDAC4 (0.34) | HDAC4HDAC2HDAC8HDAC6TRPA1 | |
| SCHEMBL4578689 | 1.00 | HDAC4 (0.34) | HDAC4HDAC2HDAC8HDAC6TRPA1 | |
| SCHEMBL20542554 | 1.00 | HDAC4 (0.34) | HDAC4HDAC2HDAC8HDAC6TRPA1 | |
| SCHEMBL3124175 | 1.00 | HDAC4 (0.34) | HDAC4HDAC2HDAC8HDAC6TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240051976-A1 | A Tracer Compound and a Preparation Method Thereof | TURUN YLIOPISTO (FI) | 2024-02-15 | — | — | US | disclosed |
| EP-4267589-A1 | A TRACER COMPOUND AND A PREPARATION METHOD THEREOF | Turun yliopisto (FI) | 2023-11-01 | — | — | EP | disclosed |
| US-11753385-B2 | Method for producing kakeromycin and derivatives thereof | OP BIO FACTORY CO., LTD. (JP) | 2023-09-12 | — | — | US | disclosed |
| CN-115160248-A | Method for producing Kakeromycin and derivatives thereof | 海洋规划生物工厂株式会社 | 2022-10-11 | — | — | CN | disclosed |
| CN-114874131-A | Method for producing Kakeromycin and derivatives thereof | 海洋规划生物工厂株式会社 | 2022-08-09 | — | — | CN | disclosed |
| CN-114835596-A | Method for producing Kakeromycin and derivatives thereof | 海洋规划生物工厂株式会社 | 2022-08-02 | — | — | CN | disclosed |
| WO-2022144501-A1 | A TRACER COMPOUND AND A PREPARATION METHOD THEREOF | TURUN YLIOPISTO (FI) | 2022-07-07 | — | — | WO | disclosed |
| CN-107709335-B | Method for producing Kakeromycin and derivatives thereof | 海洋规划生物工厂株式会社 | 2022-05-31 | — | — | CN | disclosed |
| US-20220024883-A1 | METHOD FOR PRODUCING KAKEROMYCIN AND DERIVATIVES THEREOF | OP BIO FACTORY CO., LTD. (JP) | 2022-01-27 | — | — | US | disclosed |
| EP-3263572-B1 | METHOD FOR PRODUCING KAKEROMYCIN AND DERIVATIVES THEREOF | SEED RES INSTITUTE CO LTD (JP) | 2021-12-15 | — | — | EP | disclosed |
| EP-0916668-A1 | CHEMOKINE RECEPTOR ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-05-19 | — | — | EP | disclosed |
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |
| US-4006122-A | STORAGE STABLE | THE UPJOHN COMPANY (US) | 1977-02-01 | — | — | US | disclosed |
| US-3965192-A | Hydrocarbonylation process | UNION OIL COMPANY OF CALIFORNIA (US) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11753385-B2 | Method for producing kakeromycin and derivatives thereof | ERG28, CYP51A1, NISCH | HDAC4 650/4885HDAC2 984/4885HDAC8 248/4885 |
| US-20220024883-A1 | METHOD FOR PRODUCING KAKEROMYCIN AND DERIVATIVES THEREOF | ERG28, CYP51A1, NISCH | HDAC4 650/4885HDAC2 984/4885HDAC8 248/4885 |
| US-20240051976-A1 | A Tracer Compound and a Preparation Method Thereof | TALDO1, SLCO2B1, SLCO1B1 | HDAC4 3942/4885HDAC2 2721/4885HDAC8 2559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.