Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 13/20 | 0.37 |
| ▸ | MPO | P05164 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21940573 | 0.82 | S1PR2 (0.38) | S1PR2MPOKCNH2IRAK4LRRK2 | |
| SCHEMBL21941071 | 0.78 | S1PR2 (0.34) | S1PR2 | |
| SCHEMBL20606921 | 0.78 | S1PR2 (0.49) | S1PR2 | |
| Hydrochloric Acid SCHEMBL20606941 | 0.77 | S1PR2 (0.48) | S1PR2 | |
| SCHEMBL21940574 | 0.77 | S1PR2 (0.34) | S1PR2IRAK4 | |
| SCHEMBL21940540 | 0.75 | LRRK2 (0.40) | IRAK4LRRK2 | |
| SCHEMBL21940480 | 0.71 | S1PR2 (0.41) | S1PR2MPOKCNH2 | |
| SCHEMBL21940255 | 0.70 | S1PR2 (0.37) | S1PR2MPOKCNH2 | |
| SCHEMBL21819818 | 0.69 | PRMT5 (0.39) | S1PR2 | |
| SCHEMBL21819819 | 0.68 | IRAK4 (0.38) | IRAK4LRRK2SOST |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423445-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2020-04-01 | — | — | EP | disclosed |