Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 3/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | KHK | P50053 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 5/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.30 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21940574 | 0.94 | S1PR2 (0.34) | S1PR2IRAK4WDR5 | |
| SCHEMBL21940476 | 0.82 | S1PR2 (0.37) | S1PR2IRAK4LRRK2MPOKCNH2 | |
| SCHEMBL20606887 | 0.78 | S1PR2 (0.50) | S1PR2BRD4 | |
| SCHEMBL21940540 | 0.75 | LRRK2 (0.40) | IRAK4LRRK2PRKDCBRD4CREBBP | |
| SCHEMBL21940475 | 0.70 | S1PR2 (0.42) | S1PR2 | |
| SCHEMBL21819819 | 0.70 | IRAK4 (0.38) | IRAK4LRRK2BRD4CREBBP | |
| SCHEMBL20606795 | 0.69 | S1PR2 (0.39) | S1PR2LRRK2BRD4CREBBPWDR5 | |
| SCHEMBL21940276 | 0.69 | S1PR2 (0.40) | S1PR2 | |
| SCHEMBL21940282 | 0.69 | S1PR2 (0.41) | S1PR2LRRK2MPOKCNH2 | |
| SCHEMBL21940269 | 0.66 | S1PR2 (0.34) | S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423445-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2020-04-01 | — | — | EP | disclosed |