Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 14/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21902079 | 0.87 | GRIN2B (0.64) | GRIN2BCNR2DRD4 | |
| SCHEMBL21941274 | 0.81 | GRIN2B (0.56) | GRIN2BRXRBDRD4SIGMAR1 | |
| SCHEMBL21941388 | 0.80 | RXRB (0.48) | GRIN2BCNR2RXRBDRD4SIGMAR1 | |
| SCHEMBL21902097 | 0.79 | GRIN2B (0.79) | GRIN2BRXRB | |
| SCHEMBL31663802 | 0.79 | DRD4 (0.57) | CNR2DRD4SIGMAR1 | |
| SCHEMBL1947037 | 0.79 | DRD4 (0.57) | CNR2DRD4SIGMAR1 | |
| SCHEMBL21941206 | 0.79 | DRD4 (0.47) | GRIN2BRXRBDRD4 | |
| SCHEMBL21903007 | 0.74 | GRIN2B (0.66) | GRIN2BRXRBDRD4 | |
| SCHEMBL24893024 | 0.71 | RXRB (0.67) | GRIN2BRXRBDRD4 | |
| SCHEMBL21902096 | 0.70 | GRIN2B (0.79) | GRIN2BRXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020079042-A1 | 4-PYRIDINYLMETHYL-MORPHOLINE DERIVATIVES AND THE USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-04-23 | — | — | WO | disclosed |