Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 15/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1947037 | 1.00 | DRD4 (0.57) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2933580 | 0.85 | DRD4 (0.57) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5437188 | 0.84 | DRD4 (0.56) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8719927 | 0.81 | DRD4 (0.53) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21902079 | 0.80 | GRIN2B (0.64) | DRD4CNR2 | |
| SCHEMBL13038818 | 0.80 | MPO (0.51) | DRD4DRD2DRD3 | |
| SCHEMBL5666784 | 0.79 | DRD4 (0.66) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21941810 | 0.79 | GRIN2B (0.49) | DRD4CNR2SIGMAR1 | |
| SCHEMBL31328464 | 0.78 | DRD4 (0.63) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13895166 | 0.77 | DRD4 (0.71) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4419207-B1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LTD (GB) | 2025-07-23 | — | — | EP | disclosed |