Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334930 | 0.86 | TTR (0.54) | TTRPTGER4KMODHODHESR2 | |
| SCHEMBL27878097 | 0.82 | TTR (0.54) | TTRKMODHODHPTGS1ACLY | |
| SCHEMBL18582759 | 0.79 | TTR (0.51) | TTRPTGER4KMODHODHESR2 | |
| SCHEMBL21942026 | 0.79 | TTR (0.51) | TTRPTGER4KMODHODHESR2 | |
| SCHEMBL18311196 | 0.79 | DHODH (0.43) | DHODHESR2PTGS1 | |
| SCHEMBL7827636 | 0.79 | TPMT (0.54) | TTRALDH1A1 | |
| SCHEMBL21941913 | 0.79 | CA12 (0.50) | TTRACLY | |
| SCHEMBL29446578 | 0.77 | PTPN1 (0.46) | TTRKMODHODHPTGS1 | |
| SCHEMBL6735793 | 0.77 | TTR (0.49) | TTRL3MBTL1ACLYALDH1A1 | |
| SCHEMBL2744081 | 0.77 | GRIK1 (0.56) | TTRKMOL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636637-A1 | INHIBITING FATTY ACID SYNTHASE (FASN) | Forma Therapeutics, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |