Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 4/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | CBFB | Q13951 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19776314 | 0.81 | F2RL3 (0.41) | F2RL3MAPTDHFRMTNR1AMTNR1B | |
| SCHEMBL19776230 | 0.81 | F2RL3 (0.41) | F2RL3DHFRMTNR1AMTNR1BPDE5A | |
| SCHEMBL19783346 | 0.81 | F2RL3 (0.42) | F2RL3 | |
| SCHEMBL19775903 | 0.80 | F2RL3 (0.40) | F2RL3DHFRMTNR1AMTNR1BCBFB | |
| SCHEMBL30189960 | 0.72 | F2RL3 (0.44) | F2RL3 | |
| SCHEMBL21395742 | 0.71 | F2RL3 (0.50) | F2RL3 | |
| SCHEMBL30187604 | 0.71 | F2RL3 (0.50) | F2RL3 | |
| SCHEMBL19783412 | 0.68 | F2RL3 (0.61) | F2RL3MAPT | |
| SCHEMBL23462962 | 0.68 | F2RL3 (0.55) | F2RL3 | |
| SCHEMBL2547333 | 0.66 | ALDH1A1 (0.47) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484881-B1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-04-29 | — | — | EP | disclosed |